| Catalog_no | AP1456 |
| Product_name | Rac1/cdc42 (phospho-Ser71) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Protein_name | Rac1/cdc42 (Ser71) |
| Human swiss prot no | 998 |
| Human swiss prot no | P60953 |
| Mouse gene id | 12540 |
| Mouse swiss prot no | P60766 |
| Rat gene id | 64465 |
| Rat swiss prot no | Q8CFN2 |
| immunogen | Synthesized phosho peptide around human Rac1 (Ser71) |
| Specificity | This antibody detects endogenous levels of Human Rac1/cdc42 (phospho-Ser71) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Cell division control protein 42 homolog (G25K GTP-binding protein) |
| Observed_band | 21KD |
| Background | cell division cycle 42(CDC42) Homo sapiens The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013], |
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