Catalog_noAP1458
Product_nameRad18 (phospho-Ser403) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameRAD18 RNF73
Protein_nameRad18 (Ser403)
Human swiss prot no56852
Human swiss prot noQ9NS91
Mouse gene id58186
Mouse swiss prot noQ9QXK2
immunogenSynthesized phosho peptide around human Rad18 (Ser403)
SpecificityThis antibody detects endogenous levels of Human Rad18 (phospho-Ser403)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameE3 ubiquitin-protein ligase RAD18 (EC 6.3.2.-) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73)
Observed_band56KD
BackgroundRAD18, E3 ubiquitin protein ligase(RAD18) Homo sapiens The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008],
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