Catalog_noAP1462
Product_nameRb (phospho-Ser807/811) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Mouse,Rat
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameRB1
Protein_nameRb (Ser807/811)
Human swiss prot no5925
Human swiss prot noP06400
Mouse gene id19645
Mouse swiss prot noP13405
Rat gene id24708
Rat swiss prot noP33568
immunogenSynthesized phosho peptide around human Rb (Ser807 and 811)
SpecificityThis antibody detects endogenous levels of Human Mouse Rat Rb (phospho-Ser807 or 811)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameRetinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)
Observed_band106KD
BackgroundRB transcriptional corepressor 1(RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
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