Catalog_noAP1485
Product_nameSF3B1 (phospho-Thr313) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Mouse
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameSF3B1 SAP155
Protein_nameSF3B1 (Thr313)
Human swiss prot no23451
Human swiss prot noO75533
Mouse gene id
Mouse swiss prot noQ99NB9
immunogenSynthesized phosho peptide around human SF3B1 (Thr313)
SpecificityThis antibody detects endogenous levels of Human Mouse SF3B1 (phospho-Thr313)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameSplicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Observed_band145KD
Backgroundsplicing factor 3b subunit 1(SF3B1) Homo sapiens This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
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