Catalog_noAP1492
Product_nameSHP-1 (phospho-Tyr564) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Mouse
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_namePTPN6 HCP PTP1C
Protein_nameSHP-1 (Tyr564)
Human swiss prot no5777
Human swiss prot noP29350
Mouse gene id15170
Mouse swiss prot noP29351
Rat gene id116689
Rat swiss prot noP81718
immunogenSynthesized phosho peptide around human SHP-1 (Tyr564)
SpecificityThis antibody detects endogenous levels of Human Mouse SHP-1 (phospho-Tyr564)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameTyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Observed_band65KD
Backgroundprotein tyrosine phosphatase, non-receptor type 6(PTPN6) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul
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