| Catalog_no | AP1493 |
| Product_name | SHP-2 (phospho-Tyr542) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | PTPN11 PTP2C SHPTP2 |
| Protein_name | SHP-2 (Tyr542) |
| Human swiss prot no | 5781 |
| Human swiss prot no | Q06124 |
| Mouse gene id | 19247 |
| Mouse swiss prot no | P35235 |
| Rat gene id | 25622 |
| Rat swiss prot no | P41499 |
| immunogen | Synthesized phosho peptide around human SHP-2 (Tyr542) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat SHP-2 (phospho-Tyr542) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) |
| Observed_band | 72KD |
| Background | protein tyrosine phosphatase, non-receptor type 11(PTPN11) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016], |
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