Catalog_no | AP1496 |
Product_name | Skp2 (phospho-Ser64) rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human |
Size | 100μg/50μg/20μg |
Price | 2200.00/1200.00/560.00 |
Gene_name | SKP2 FBXL1 |
Protein_name | Skp2 (Ser64) |
Human swiss prot no | 6502 |
Human swiss prot no | Q13309 |
Mouse gene id | 27401 |
Mouse swiss prot no | Q9Z0Z3 |
immunogen | Synthesized phosho peptide around human Skp2 (Ser64) |
Specificity | This antibody detects endogenous levels of Human Skp2 (phospho-Ser64) |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:1000-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
othername | S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2) |
Observed_band | 47KD |
Background | S-phase kinase associated protein 2(SKP2) Homo sapiens This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and int |
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