Catalog_noAP1514
Product_nameStat3 (phospho-Tyr705) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Mouse,Rat
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameSTAT3 APRF
Protein_nameStat3 (Tyr705)
Human swiss prot no6774
Human swiss prot noP40763
Mouse gene id20848
Mouse swiss prot noP42227
Rat gene id25125
Rat swiss prot noP52631
immunogenSynthesized phosho peptide around human Stat3 (Tyr705)
SpecificityThis antibody detects endogenous levels of Human Mouse Rat Stat3 (phospho-Tyr705)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameSignal transducer and activator of transcription 3 (Acute-phase response factor)
Observed_band88KD
Backgroundsignal transducer and activator of transcription 3(STAT3) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper
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