| Catalog_no | AP1522 |
| Product_name | TAK1 (phospho-Ser412) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | MAP3K7 TAK1 |
| Protein_name | TAK1 (Ser412) |
| Human swiss prot no | 6885 |
| Human swiss prot no | O43318 |
| Mouse gene id | 26409 |
| Mouse swiss prot no | Q62073 |
| Rat gene id | 100910771 |
| Rat swiss prot no | P0C8E4 |
| immunogen | Synthesized phosho peptide around human TAK1 (Ser412) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat TAK1 (phospho-Ser412) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) |
| Observed_band | 70KD |
| Background | mitogen-activated protein kinase kinase kinase 7(MAP3K7) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008], |
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