Catalog_noAP1537
Product_nameTTF-1 (phospho-Ser327) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameNKX2-1 NKX2A TITF1 TTF1
Protein_nameTTF-1 (Ser327)
Human swiss prot no7080
Human swiss prot noP43699
Mouse gene id21869
Mouse swiss prot noP50220
Rat swiss prot noP23441
immunogenSynthesized phosho peptide around human TTF-1 (Ser327)
SpecificityThis antibody detects endogenous levels of Human TTF-1 (phospho-Ser327)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameHomeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1)
Observed_band38KD
BackgroundNK2 homeobox 1(NKX2-1) Homo sapiens This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],
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