Catalog_noAP1545
Product_nameVASP (phospho-Ser239) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Mouse,Rat
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameVASP
Protein_nameVASP (Ser239)
Human swiss prot no7408
Human swiss prot noP50552
Mouse gene id22323
Mouse swiss prot noP70460
immunogenSynthesized phosho peptide around human VASP (Ser239)
SpecificityThis antibody detects endogenous levels of Human Mouse Rat VASP (phospho-Ser239)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameVasodilator-stimulated phosphoprotein (VASP)
Observed_band46+50KD
Backgroundvasodilator-stimulated phosphoprotein(VASP) Homo sapiens Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008],
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