| Catalog_no | AP1557 |
| Product_name | β-Arrestin 1 (phospho-Ser412) rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Mouse,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2200.00/1200.00/560.00 |
| Gene_name | ARRB1 ARR1 |
| Protein_name | β-Arrestin 1 (Ser412) |
| Human swiss prot no | 408 |
| Human swiss prot no | P49407 |
| Mouse gene id | 109689 |
| Mouse swiss prot no | Q8BWG8 |
| Rat gene id | 25387 |
| Rat swiss prot no | P29066 |
| immunogen | Synthesized phosho peptide around human β-Arrestin 1 (Ser412) |
| Specificity | This antibody detects endogenous levels of Human Mouse Rat β-Arrestin 1 (phospho-Ser412) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1:1000-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| othername | Beta-arrestin-1 (Arrestin beta-1) |
| Observed_band | 47KD |
| Background | arrestin beta 1(ARRB1) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011], |
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