Catalog_noAP1558
Product_nameβ-Catenin (phospho-Ser675) rabbit pAb
Category抗原抗体
ApplicationsWB
ReactivityHuman,Mouse,Rat
Size100μg/50μg/20μg
Price2200.00/1200.00/560.00
Gene_nameCTNNB1 CTNNB OK/SW-cl.35 PRO2286
Protein_nameβ-Catenin (Ser675)
Human swiss prot no1499
Human swiss prot noP35222
Mouse gene id12387
Mouse swiss prot noQ02248
Rat gene id84353
Rat swiss prot noQ9WU82
immunogenSynthesized phosho peptide around human β-Catenin (Ser675)
SpecificityThis antibody detects endogenous levels of Human Mouse Rat β-Catenin (phospho-Ser675)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SourceRabbit
DilutionWB 1:1000-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage_stability-20°C/1 year
othernameCatenin beta-1 (Beta-catenin)
Observed_band100KD
Backgroundcatenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
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