Catalog_no | AP1558 |
Product_name | β-Catenin (phospho-Ser675) rabbit pAb |
Category | 抗原抗体 |
Applications | WB |
Reactivity | Human,Mouse,Rat |
Size | 100μg/50μg/20μg |
Price | 2200.00/1200.00/560.00 |
Gene_name | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 |
Protein_name | β-Catenin (Ser675) |
Human swiss prot no | 1499 |
Human swiss prot no | P35222 |
Mouse gene id | 12387 |
Mouse swiss prot no | Q02248 |
Rat gene id | 84353 |
Rat swiss prot no | Q9WU82 |
immunogen | Synthesized phosho peptide around human β-Catenin (Ser675) |
Specificity | This antibody detects endogenous levels of Human Mouse Rat β-Catenin (phospho-Ser675) |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source | Rabbit |
Dilution | WB 1:1000-2000 |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration | 1 mg/ml |
Storage_stability | -20°C/1 year |
othername | Catenin beta-1 (Beta-catenin) |
Observed_band | 100KD |
Background | catenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016], |
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