Catalog_no | BD-PD400082 |
Product_name | Anti-SARS-CoV-2 (2019-nCoV) Nucleocapsid Magnetic Beads Immunoprecipitation (IP) Kit |
Category | 冠状病毒产品 |
Applications | Immunoprecipitation (IP), Minimum Protein Purification |
Size | 20T/100T |
Price | 2860.00/9300.00 |
immunogen | Recombinant SARS-CoV-2 / 2019-nCoV Nucleocapsid Protein |
Specificity | SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP Protein |
Background | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
预测N端 | Produced in rabbits immunized with purified, recombinant SARS-CoV-2 / 2019-nCoV Nucleocapsid Protein (Catalog#40588-V08B; YP_009724397.2(335Gly/Ala); Met1-Ala419). The specific IgG was purified by SARS-CoV-2 / 2019-nCoV Nucleocapsid affinity chromato |
Instructions |
查看与下载 |
Share |
|