ALDH6A1 Antibody

日期:2020-08-01 00:36 人气:
Catalog_no AB0685
Product_name ALDH6A1 Antibody
Category 抗原抗体
Applications WB, IHC-P, FC
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN
Specificity This ALDH6A1 antibody is generated from mouse immunized with ALDH6A1 recombinant protein.
Dilution IF,1:25;IHC-P,1:25;WB,1:1000;IHC-P,1:25;
Purification Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
othername Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating], Aldehyde dehydrogenase family 6 member A1, ALDH6A1, MMSDH
Isotype IgG1,IgK
Background This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
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