MCAF2 Antibody (Center)

日期:2020-08-01 00:36 人气:
Catalog_no AB0786
Product_name MCAF2 Antibody (Center)
Category 抗原抗体
Applications WB
Reactivity H, M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:318-347
Specificity This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human MCAF2.
Dilution WB,1:1000;WB,1:1000;IHC-P,1:50~100;FC,1:10~50;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername Activating transcription factor 7-interacting protein 2, ATF7-interacting protein 2, MBD1-containing chromatin-associated factor 2, ATF7IP2, MCAF2
Isotype Rabbit Ig
Background Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
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