CFH Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB0853
Product_name	CFH Antibody (Center)
Category	抗原抗体
Applications	FC, WB
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:751-780
Specificity	This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH.
Dilution	IF,1:25;IF,1:25;WB,1:2000;WB,1:2000;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Complement factor H, H factor 1, CFH, HF, HF1, HF2
Isotype	Rabbit Ig
Background	This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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