ERCC8 Antibody (Center)

日期:2020-08-01 00:36 人气:
Catalog_no AB0855
Product_name ERCC8 Antibody (Center)
Category 抗原抗体
Applications WB, IHC-P, FC
Reactivity H, M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:210-238
Specificity This ERCC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8.
Dilution WB,1:1000;IHC-P,1:50~100;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA, ERCC8, CKN1, CSA
Isotype Rabbit Ig
Background This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
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