CE164 Antibody (N-term)
日期:2020-08-01 00:36 人气:
Catalog_no | AB0859 |
Product_name | CE164 Antibody (N-term) |
Category | 抗原抗体 |
Applications | WB, FC |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:246-274 |
Specificity | This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164. |
Dilution | WB,1:1000;FC,1:10~50; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Centrosomal protein of 164 kDa, Cep164, CEP164, KIAA1052, NPHP15 |
Isotype | Rabbit Ig |
Background | Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1. |
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