CE164 Antibody (N-term)

日期:2020-08-01 00:36 人气:
Catalog_no AB0859
Product_name CE164 Antibody (N-term)
Category 抗原抗体
Applications WB, FC
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:246-274
Specificity This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164.
Dilution WB,1:1000;FC,1:10~50;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername Centrosomal protein of 164 kDa, Cep164, CEP164, KIAA1052, NPHP15
Isotype Rabbit Ig
Background Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1.
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