NUDT15 Antibody (C-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB0871
Product_name	NUDT15 Antibody (C-term)
Category	抗原抗体
Applications	WB, FC
Reactivity	H, M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:89-118
Specificity	This NUDT15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the C-terminal region of human NUDT15.
Dilution	WB,1:500;WB,1:1000;WB,1:1000;IHC-P,1:50~100;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Probable 8-oxo-dGTP diphosphatase NUDT15, 8-oxo-dGTPase NUDT15,8-dihydro-8-oxoguanine-triphosphatase NUDT15, MutT homolog 2, MTH2, Nucleoside diphosphate-linked moiety X motif 15, Nudix motif 15, NUDT15, MTH2
Isotype	Rabbit Ig
Background	Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
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