GAD2 Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB0885
Product_name	GAD2 Antibody (Center)
Category	抗原抗体
Applications	FC, WB
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:109-138
Specificity	This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2.
Dilution	WB,1:1000;WB,1:1000;IHC-P,1:50~100;IF,1:10~50;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, GAD2, GAD65
Isotype	Rabbit Ig
Background	This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
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