CHMP2B Antibody (N-term)

日期:2020-08-01 00:36 人气:
Catalog_no AB1163
Product_name CHMP2B Antibody (N-term)
Category 抗原抗体
Applications WB, FC, IHC-P
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:1-30
Specificity This CHMP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B.
Dilution WB,1:1000;IHC-P,1:10~50;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername Charged multivesicular body protein 2b, CHMP25, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, CHMP2B
Isotype Rabbit Ig
Background This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
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