Mouse Abl1 Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB1247
Product_name	Mouse Abl1 Antibody (Center)
Category	抗原抗体
Applications	WB
Reactivity	M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	MOUSE:613-641
Specificity	This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1.
Dilution	WB,1:1000;IHC-P,1:10~50;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150, Abl1, Abl
Isotype	Rabbit Ig
Background	Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
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