Mouse Dyrk2 Antibody (C-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB1272
Product_name	Mouse Dyrk2 Antibody (C-term)
Category	抗原抗体
Applications	WB
Reactivity	H, M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	MOUSE:521-549
Specificity	This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
Dilution	IHC-P,1:100;WB,1:2000;WB,1:8000;WB,1:1000;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Dual specificity tyrosine-phosphorylation-regulated kinase 2, Dyrk2 {ECO:0000312\|MGI:MGI:1330301}
Isotype	Rabbit Ig
Background	Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
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