Mouse Ern1 Antibody (C-term)
日期:2020-08-01 00:36 人气:
Catalog_no | AB1309 |
Product_name | Mouse Ern1 Antibody (C-term) |
Category | 抗原抗体 |
Applications | WB |
Reactivity | M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | MOUSE:827-855 |
Specificity | This Mouse Ern1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 827-855 amino acids from the C-terminal region of mouse Ern1. |
Dilution | WB,1:1000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, 3126-, Ern1 {ECO:0000312|MGI:MGI:1930134} |
Isotype | Rabbit Ig |
Background | Ern1 senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. |
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