CTDSP2 Antibody (N-term)
日期:2020-08-01 00:36 人气:
Catalog_no | AB1345 |
Product_name | CTDSP2 Antibody (N-term) |
Category | 抗原抗体 |
Applications | WB |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:11-39 |
Specificity | This CTDSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human CTDSP2. |
Dilution | WB,1:1000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, Nuclear LIM interactor-interacting factor 2, NLI-interacting factor 2, Protein OS-4, Small C-terminal domain phosphatase 2, Small CTD phosphatase 2, SCP2, CTDSP2, NIF2, OS4, SCP2 |
Isotype | Rabbit Ig |
Background | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
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