Connexin 31 Antibody (C-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB1452
Product_name	Connexin 31 Antibody (C-term)
Category	抗原抗体
Applications	WB
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:204-233
Specificity	This Connexin 31 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204~233 amino acids from the C-terminal region of human GJB3.
Dilution	WB,1:1000;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
othername	Gap junction beta-3 protein, Connexin-31, Cx31, GJB3, CX31
Isotype	Rabbit Ig
Background	Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
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