RIC8A Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB1592
Product_name	RIC8A Antibody (Center)
Category	抗原抗体
Applications	WB
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:244-272
Specificity	This RIC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-272 amino acids from the Central region of human RIC8A.
Dilution	WB,1:1000;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Synembryn-A, Protein Ric-8A, RIC8A
Isotype	Rabbit Ig
Background	Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
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