ASB2 Antibody (N-term)

日期:2020-08-01 00:36 人气:
Catalog_no AB1606
Product_name ASB2 Antibody (N-term)
Category 抗原抗体
Applications WB
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:58-86
Specificity This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
Dilution WB,1:1000;WB,1:1000;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername Ankyrin repeat and SOCS box protein 2, ASB-2, ASB2
Isotype Rabbit Ig
Background The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
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