Mouse Tbk1 Antibody (N-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB1617
Product_name	Mouse Tbk1 Antibody (N-term)
Category	抗原抗体
Applications	WB
Reactivity	M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	MOUSE:8-35
Specificity	This Mouse Tbk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1.
Dilution	WB,1:1000;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername	Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1
Isotype	Rabbit Ig
Background	Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
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