NKX2-5 Antibody (Center)

日期:2020-08-01 00:36 人气:
Catalog_no AB1630
Product_name NKX2-5 Antibody (Center)
Category 抗原抗体
Applications WB
Reactivity H, M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:2-5
Specificity This NKX2-5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the Central region of human NKX2-5.
Dilution WB,1:2000;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername Homeobox protein Nkx-25, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, NKX2-5, CSX, NKX25, NKX2E
Isotype Rabbit Ig
Background This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
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