Mouse Txnip Antibody (Center)

日期:2020-08-01 00:36 人气:
Catalog_no AB2023
Product_name Mouse Txnip Antibody (Center)
Category 抗原抗体
Reactivity M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen MOUSE:116-145
Specificity This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
Dilution IHC-P,1:100;WB,1:2000;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othername Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Isotype Rabbit Ig
Background May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
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