PAD4 Antibody (C-term)

日期:2020-08-01 00:36 人气:
Catalog_no AB2085
Product_name PAD4 Antibody (C-term)
Category 抗原抗体
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:512-544
Specificity This PAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 512-544 amino acids from the C-terminal region of human PAD4.
Dilution WB,1:1000;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
othername Protein-arginine deiminase type-4, HL-60 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, PADI4, PADI5, PDI5
Isotype Rabbit Ig
Background PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.
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