DHCR24 Antibody (N-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB2121
Product_name	DHCR24 Antibody (N-term)
Category	抗原抗体
Reactivity	H, M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:57-87
Specificity	This DHCR24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-87 amino acids from the N-terminal region of human DHCR24.
Dilution	WB,1:1000;WB,1:1000;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
othername	Delta(24)-sterol reductase, 24-dehydrocholesterol reductase, 3-beta-hydroxysterol delta-24-reductase, Diminuto/dwarf1 homolog, Seladin-1, DHCR24, KIAA0018
Isotype	Rabbit Ig
Background	DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
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