Phospho-mouse BAD(S112) Antibody

日期:2020-08-01 00:36 人气:
Catalog_no AB2156
Product_name Phospho-mouse BAD(S112) Antibody
Category 抗原抗体
Reactivity M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen MOUSE
Specificity This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S112 of mouse BAD.
Dilution DB,1:500;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
othername Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6
Isotype Rabbit Ig
Background BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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