Phospho-mouse TSC1(S1138) Antibody

日期：2020-08-01 00:36　人气：

Catalog_no	AB2210
Product_name	Phospho-mouse TSC1(S1138) Antibody
Category	抗原抗体
Reactivity	M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	MOUSE
Specificity	This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1138 of mouse TSC1.
Dilution	DB,1:500;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
othername	Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Isotype	Rabbit Ig
Background	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
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