Phospho-mouse TSC1(T416) Antibody

日期:2020-08-01 00:36 人气:
Catalog_no AB2211
Product_name Phospho-mouse TSC1(T416) Antibody
Category 抗原抗体
Reactivity M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen MOUSE
Specificity This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T416 of mouse TSC1.
Dilution DB,1:500;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
othername Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Isotype Rabbit Ig
Background In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
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