SIRT6 Antibody (C-term)
日期:2020-08-01 00:36 人气:
Catalog_no | AB2377 |
Product_name | SIRT6 Antibody (C-term) |
Category | 抗原抗体 |
Reactivity | H, M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:290-319 |
Specificity | This SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the C-terminal region of human SIRT6. |
Dilution | WB,1:500;IHC-P,1:50~100;WB,1:1000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
othername | NAD-dependent protein deacetylase sirtuin-6, 351-, Regulatory protein SIR2 homolog 6, SIR2-like protein 6, SIRT6, SIR2L6 |
Isotype | Rabbit Ig |
Background | SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. |
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