CKB Antibody (N-term)

日期:2020-08-01 00:36 人气:
Catalog_no AB2464
Product_name CKB Antibody (N-term)
Category 抗原抗体
Reactivity H, M
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN:1-30
Specificity This CKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CKB.
Dilution WB,1:1000;WB,1:1000;
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
othername Creatine kinase B-type, B-CK, Creatine kinase B chain, CKB, CKBB
Isotype Rabbit Ig
Background Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKB isoform, present in many tissues but especially brain, is a cytoplasmic enzyme involved in energy homeostasis. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
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