IMPDH2 Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB2506
Product_name	IMPDH2 Antibody (Center)
Category	抗原抗体
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:180-210
Specificity	This IMPDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human IMPDH2.
Dilution	WB,1:1000;IHC-P,1:50~100;FC,1:10~50;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
othername	Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMP dehydrogenase 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPD 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH-II, IMPDH2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPD2
Isotype	Rabbit Ig
Background	IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
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