CAMK2A Antibody (C-term E370)
日期:2020-08-01 00:36 人气:
Catalog_no | AB2509 |
Product_name | CAMK2A Antibody (C-term E370) |
Category | 抗原抗体 |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:344-371 |
Specificity | This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human CAMK2A. |
Dilution | WB,1:1000;WB,1:1000;IHC-P,1:10~50; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
othername | Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968 |
Isotype | Rabbit Ig |
Background | CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. |
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