NRAS Antibody (N-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB2539
Product_name	NRAS Antibody (N-term)
Category	抗原抗体
Reactivity	H, M, Rat
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN:72-101
Specificity	This NRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human NRAS.
Dilution	WB,1:1000;WB,1:1000;FC,1:10~50;IF,1:10~50;
Purification	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
othername	GTPase NRas, Transforming protein N-Ras, NRAS, HRAS1
Isotype	Rabbit Ig
Background	NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
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