Mouse Cbx7 Antibody (C-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3024
Product_name	Mouse Cbx7 Antibody (C-term)
Category	抗原抗体
Reactivity	H, M, Rat
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7.
Dilution	WB,1:1000;
othername	Chromobox protein homolog 7, Cbx7, D15Ertd417e
Isotype	Rabbit Ig
Background	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trimethylated lysine residues in other proteins (in vitro). Binds non-coding, single-stranded RNA. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
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