Mouse Hes1 Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3064
Product_name	Mouse Hes1 Antibody (Center)
Category	抗原抗体
Reactivity	M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1.
Dilution	WB,1:1000;
othername	Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1
Isotype	Rabbit Ig
Background	Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
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