(Mouse) Smad2 Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3106
Product_name	(Mouse) Smad2 Antibody (Center)
Category	抗原抗体
Reactivity	H, M, Rat
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This mouse Smad2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-232 amino acids from the Central region of mouse Smad2.
Dilution	WB,1:500-1:1000;
othername	Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, Mad-related protein 2, mMad2, SMAD family member 2, SMAD 2, Smad2, Smad2, Madh2, Madr2
Isotype	Rabbit Ig
Background	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity).
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