ANAPC2 Antibody (C-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3149
Product_name	ANAPC2 Antibody (C-term)
Category	抗原抗体
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This ANAPC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of human ANAPC2.
Dilution	IF,1:25;IHC-P,1:25;WB,1:1000;
othername	Anaphase-promoting complex subunit 2, APC2, Cyclosome subunit 2, ANAPC2, APC2, KIAA1406
Isotype	Rabbit Ig
Background	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
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