(Mouse) Pdx1 Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3156
Product_name	(Mouse) Pdx1 Antibody (Center)
Category	抗原抗体
Reactivity	M
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This Mouse Pdx1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 136-169 amino acids from the Central region of Mouse Pdx1.
Dilution	IF,1:25;WB,1:1000;
othername	Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox 1, IDX-1, Somatostatin-transactivating factor 1, STF-1, Pdx1, Ipf1
Isotype	Rabbit Ig
Background	Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
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