CBX7 Antibody (C-term)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3200
Product_name	CBX7 Antibody (C-term)
Category	抗原抗体
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This CBX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-201 amino acids from the C-terminal region of human CBX7.
Dilution	WB,1:1000;WB,1:500;
othername	Chromobox protein homolog 7, CBX7
Isotype	Rabbit Ig
Background	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
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