KDM6A Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3263
Product_name	KDM6A Antibody (Center)
Category	抗原抗体
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This KDM6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 797-832 amino acids from the Central region of human KDM6A.
Dilution	WB,1:2000;
othername	Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein, KDM6A, UTX
Isotype	Rabbit Ig
Background	Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
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