PCGF6 Antibody (Center)

日期:2020-08-01 00:36 人气:
Catalog_no AB3273
Product_name PCGF6 Antibody (Center)
Category 抗原抗体
Reactivity Rat
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN
Specificity This PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 215-249 amino acids from the Central region of human PCGF6.
Dilution WB,1:2000;
othername Polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134
Isotype Rabbit Ig
Background Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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